Sorry you are having issues. I found this bit of info, but you properly already have it, but here it is anyway:
Make sure that you are not using a USB cable longer than 3 meters
Try using a different USB cable
If you were using a USB cable that didn’t come with the unit, try using the one that came with it.
3. USB Hub
Make sure that you are plugged directly into your computer's USB ports and NOT a USB hub.
You are able to use a thunderbolt hub without any issues
4. Reset the mixer configuration
Make sure the iD app is completely quitted (DONT just close the window) with the iD disconnected
On a Mac, go to ~/Library/Application Support/Audient/iD14
On a PC, go to (C:) > Users > yourusername > AppData > Roaming > Audient > iD > state.xml
Delete the state.xml file
Restart your computer and iD14 and relaunch the iD application
5. Reinstall app
Uninstall the iD software
Reboot your computer
Download the latest version from the Downloads page - www.audient.com/downloads/iD14
Reinstall the software
6. Check for Driver Conflicts
Very occasionally older drivers from other audio interfaces can clash with the iD22 drivers causing poor performance. Double check that there aren't any drivers installed on your system that aren't currently in use and uninstall them.
If you are still having issues please get in contact with our Technical Support team by creating a support ticket, or by emailing support@audient.com