Oh no, guitars sound as they should I think, just the bass Direct sounds kinda muddy, and Darkglass brings it to life, and I tested this using now Amplitube afterwards in the chain, sounds lovely, finally. With guitars I have no issue in the muddy part, although I haven't found my tone.
On the other side, Neuraldsp sound pretty good, but no matter what I do they sound too hot, even if I lower the input a lot, I feel I can't get a mid-way saturation/distortion. But these amps sound crisp as hell, that's for sure.