I know this is an old thread, but I just wondered if anyone who had/has had this problem was using a USB connector for the keyboard or if it was all MIDI? My little NanoKey is having this issue and I have it patched USB. None of the latency settings has been able to get me the response I need. I wonder if instead of patching to the computer USB, if I bought a MIDI adapter and patched into my MOTU interface it f that would help? I used to have no problems w/ latency using my NanoKey keyboard via a much older version of Sonar.