I would say my non-stoppable playback issue has something to do with near-dropout situations, when running on the edge, so to speak. Then again, it might happen with smaller projects and less tracks and plugins, but less likely. It has been like that with Windows 8.1 and all incarnations of Windows 10 up to 1809, which I currently have, which leads me to believe it's something with the Focusrite drivers after all. It's happened with various versions of Focusrite drivers as well and newer really gone away completely. I have to say, that the current driver version 4.36.5 and the newest CbB versions have been working the best, even if the driver it's for 2nd generation Scarletts. 😬
The unstoppable playback is like a "runaway situation" where the time display just goes on and there might be no sound at all or a very quick stuttering noise. The transport buttons stay enabled but don't do anything. In most cases clicking the input echo button makes the driver to come to its senses and control is regained without killing the process.
Oh, and I'm currently running (the latest) CbB version on an Asus A75VJ laptop with an i7 CPU, 1TB Samsung SDD and 8 GB of RAM. It's an older setup but works quite ok anyway with the SDD. I've also moved away from using BitBridged 32-bit plugins, which may have had an affect as well.