Hi Stevie and John,
Found my problem, I had not selected the correct output in Tracks under the Audio Outputs - selected - ASIO4All v2HDA Primary ouput 1 , ( previously it was showing Master ) and then I clicked on various instruments in the drum set that I'd previously loaded, I first used my mouse and got the sound ok and pleased to say likewise the sounds would also play using the correct keys on the synth keyboard.
So I then saved the page as a project and then reopened it, but strangely got the same warning message " Silent Buses Detected", but I then went into the saved project and it played the sounds ok as before. ?