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Craig Anderton's post in Can't change presets in Amplitube 5 when running in Cakewalk? was marked as the answer
IIRC AmpliTube is one of the (many) amp sims that doesn't respond to program changes when loaded as a VST3. The VST2 version should work. I believe this has something to do with changes in the VST3 spec, not Cakewalk or AmpliTube.