Thank you Noel. Unfortunately there's still no sound. In addition, now the iRig Pro i/o signal light only shows a signal light for a few seconds after pressing Echo/Input monitoring.
I've updated the iRig firmware and the iRig driver, rebooted the pc several times.
The Cakewalk version running shows 2020.10 Build 075, 64 bit)
Any suggestions and would you know whether you've tested the iRig Pro i/o at your end (it's quite a popular device I believe) .