Thank you for the responses. I appreciate you guys taking the time.
sealesb,
I checked in my Device Manager and under Sound, Video and Game Controllers were two Focusrite drivers, one named Focusrite USB Audio and the other Focusrite USB Midi. Both listed Driver Provider as Focusrite. Under Audio Inputs and Outputs, there were two entries labels, identically, Focusrite USB (Focusrite USB Audio). Those listed their driver provider as Microsoft; my heart leapt! Could this be the answer? I disabled both of those drivers and restarted. No dice. Were these the right things to check? Is there another place to look? When that issue popped up for you, you said it was a result of a Windows update. Did it occur right after the update? That is one of the things I'm so frustrated by, I hadn't updated anything or changed any settings prior to this issue. (By the way, Chuck E Baby, in an effort to make my system as stable as possible, I have my computer set to never go to sleep, I even went so far as to turn off all of Window's system noises (dings, beeps, et al.)) I've also messed around with different ASIO settings, so I'm getting the right dialog box but those changes don't seem to have any effect.
msmcleod,
I went through to make sure there weren't any mixing plugins active and didn't find any. I did have several instances of Melodyne running, but in my initial attempts to solve the problem, I archived all of those tracks.
I'm going to continue struggling with this today, so if any of you can recommend another place to look for the driver issue, I'm all ears. Or if you have any other ideas at all. Thank you again for taking the time to respond, it was very kind of all of you.
Thanks,
Ryan